splinetrials

cranv0.1.1

Facilitate Clinical Trials Analysis Using Natural Cubic Splines. Create mixed models with repeated measures using natural cubic splines applied to an observed continuous time variable, as described by Donohue et al. (2023) <doi:10.1002/pst.2285>. Iterate through multiple covariance structure types until one converges. Categorize observed time according to schedul

License Apache License (>= 2)0 versions1 maintainers7 deps45 weekly dl
NikKrieger/splinetrials
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First published · 2026-01-19 13:31:57

Last updated · 2026-01-19T12:20:09+00:00