{"package":"nlmixr2est","ecosystem":"cran","latest_version":"5.0.2","description":"Nonlinear Mixed Effects Models in Population PK/PD, Estimation Routines. Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in th","license":"GPL (>= 3)","license_risk":"unknown","commercial_use_notes":"verify manually — license not parseable / not declared.","homepage":"https://nlmixr2.github.io/nlmixr2est/","repository":"https://github.com/nlmixr2/nlmixr2est","downloads_weekly":332,"health":{"score":45,"risk":"high","breakdown":{"maintenance":15,"popularity":3,"security":25,"maturity":0,"community":2},"deprecated":false,"max_score":100},"vulnerabilities":{"count":0,"critical":0,"high":0,"medium":0,"low":0,"details":[]},"versions":{"latest":"5.0.2","total_count":0,"recent":[]},"metadata":{"deprecated":false,"deprecated_message":null,"maintainers_count":1,"first_published":"2025-11-28 19:52:15","last_published":"2025-11-28T18:20:02+00:00","dependencies_count":20,"dependencies":["nlmixr2data","backports","checkmate","cli","graphics","knitr","lbfgsb3c","lotri","magrittr","Matrix","methods","minqa","n1qn1","nlme","Rcpp","rex","rxode2","stats","symengine","utils"]},"github_stats":null,"bundle":null,"typescript":null,"known_issues":{"bugs_count":0,"bugs_severity":{},"status_breakdown":{},"link":null,"scope":"none"},"historical_compromise":null,"recommendation":{"action":"safe_to_use","issues":[],"use_version":"5.0.2","version_hint":null,"summary":"nlmixr2est@5.0.2 is safe to use (health: 45/100)"},"version_scoped":null,"requested_version":null,"_cache":"hit","_response_ms":0,"_powered_by":"depscope.dev — free package intelligence for AI agents","typosquat":{"is_suspected":false},"maintainer_trust":{"available":false},"malicious":{"is_malicious":false},"scorecard":{"available":false},"quality":{"available":false}}